学科紹介
学科紹介
齋藤 伸吾
齋藤 伸吾 | |
SAITO Shingo | |
専門分野 | 分析化学 |
職位 | 教授 |
学位 | 博士(工学) |
担当科目 | 分析化学演習 |
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経歴 | 1996年 東北大学工学部分子化学工学科卒業 2017年 埼玉大学大学院理工学研究科 教授 |
研究紹介 | 電気泳動法(キャピラリー電気泳動法やゲル電気泳動法)を用いる特殊な分離法によって,新規機能性分子を発見したり,創り出すことを行っている。近年は,タンパク質結合型金属イオンのスペシエーション(化学種同定)を可能とするゲル電気泳動法や,細菌類や分子を認識可能な核酸(DNAアプタマー)の発見法の開発を行っている。 |
研究業績(論文) | Sumika Nakano, Shingo Saito* et al., "Stoichiometry between Humate Unit Molecules and Metal ions in Supramolecular Assembly Induced by Cu2+ and Tb3+ Measured by Gel Electrophoresis Techniques," Environmental Science & Technology, 55, 15172-15180 (2021).
Shingo Saito* et al., "Single-Round DNA Aptamer Selection by Combined Use of
Capillary Electrophoresis and Next Generation Sequencing: An Aptaomics
Approach for Identifying Unique Functional Protein-Binding DNA Aptamers,"
K. Marumo, S. Saito* et al., "Advanced Gel Electrophoresis Techniques Reveal Heterogeneity of Humic Acids Based on Molecular Weight Distributions of Kinetically Inert Cu2+-Humate Complexes," Environmental Science & Technology, 53 (24), 14507-14515 (2019).
J. Ishikawa, S. Saito* et al., "Two-dimensional Polyacrylamide Gel Electrophoresis for Metalloprotein Analysis Based on Differential Chemical Structure Recognition by CBB Dye," Scientific Reports, 9,10566 (2019).
T. Haraga, S. Saito* et al., "Safe and rapid development of capillary electrophoresis for ultratrace uranyl ions in radioactive samples from nuclear power facilities by way of fluorescent probe selection for actinide ions from a chemical library," Analytica Chimica Acta, 1032, 188-196 (2018).
K. Hirose, S. Saito* et al., "A single-round selection of selective DNA aptamers for mammalian cells by polymer-enhanced capillary transient isotachophoresis," Analyst, 142(21), 4030-4038 (2017).
S. Saito* et al., "Rapid Acquisition of High-Affinity DNA Aptamer Motifs Recognizing Microbial Cell Surfaces Using Polymer-Enhanced Capillary Transient Isotachophoresis," Chemical Communications, 52, 461-464 (2016).
K. Ouchi, S. Saito* et al.,Molecular Design of Boronic Acid-Functionalized Squarylium Cyanine Dyes for Multiple Discriminant Analysis of Sialic Acid in Biological Samples: Selectivity Toward Monosaccharides Controlled by Different Alkyl Side Chain Lengths," Analytical Chemistry, 87, 1933-1940 (2015).
S. Saito* et al., “Separation of Metalloproteins Using Novel Metal Ion Contaminant Sweeping Technique
K. Ouchi, S. Saito,* M. Shibukawa, “A New Molecular Motif for Recognizing Sialic Acid Using Emissive Lanthanide-Macrocyclic Polyazacarboxylate Complexes: Acid-Dissociation of A Coordinated Water Molecule Controls Selectivity,” Inorganic Chemistry, 52(11), 6239-6241 (2013).
S. Saito et al., “On-Column Labeling of Gram-Positive bacteria with a Novel Boronic Acid Functionalized Squarylium Cyanine Dye for Analysis by Polymer-Enhanced Capillary Transient Isotachophoresis,” Analytical Chemistry, 84, 2454-2458 (2012). |
所属学会・協会 | 分析化学会 日本電気泳動学会 |
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